Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

8.8K
Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
8.8K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

3.1K
3.1K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

2.7K
2.7K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

7.4K
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
7.4K
Sustainable Development01:43

Sustainable Development

15.2K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K
Introduction to Epidemiology01:26

Introduction to Epidemiology

1.9K
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of the first booster vaccine against SARS-CoV-2 in Chile.

Infectious Disease Modelling·2026
Same author

Natural population dynamics of Asian citrus psyllid, Diaphorina citri, and its control based on pheromone trapping.

Mathematical biosciences·2025
Same author

Assessment of Vegetable Species for Microgreen Production in Unheated Greenhouses: Yield, Nutritional Composition, and Sensory Perception.

Plants (Basel, Switzerland)·2024
Same author

Comparing the long-term persistence of different Wolbachia strains after the release of bacteria-carrying mosquitoes.

Mathematical biosciences·2024
Same author

Monotonicity properties arising in a simple model of <i>Wolbachia</i> invasion for wild mosquito populations.

Mathematical biosciences and engineering : MBE·2023
Same author

A synthesized model of tuberculosis transmission featuring treatment abandonment.

Mathematical biosciences and engineering : MBE·2022

Related Experiment Video

Updated: Feb 10, 2026

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
10:11

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

19.7K

Sustainable thresholds for cooperative epidemiological models.

Edwin Barrios1, Pedro Gajardo2, Olga Vasilieva1

  • 1Departamento de Matemáticas, Universidad del Valle, Calle 13 No. 100-00, Cali 760032, Colombia.

Mathematical Biosciences
|May 26, 2018
PubMed
Summary

This study presents a novel method for calculating sustainable thresholds in epidemiological models. This approach aids in cost-effective decision-making by balancing disease control constraints and outcomes.

Keywords:
Control theoryDengueEpidemiologySustainable thresholdsViability theory

More Related Videos

Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test
08:52

Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test

Published on: April 21, 2021

5.5K
Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
10:05

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Published on: January 27, 2018

10.2K

Related Experiment Videos

Last Updated: Feb 10, 2026

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
10:11

Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies

Published on: October 22, 2014

19.7K
Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test
08:52

Psychophysical Tracking Method to Assess Taste Detection Thresholds in Children, Adolescents, and Adults: The Taste Detection Threshold TDT Test

Published on: April 21, 2021

5.5K
Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
10:05

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Published on: January 27, 2018

10.2K

Area of Science:

  • Epidemiology
  • Mathematical Biology
  • Control Theory

Background:

  • Compartmental models are widely used in epidemiology to study disease dynamics.
  • Control strategies are essential for managing infectious disease outbreaks.
  • Determining sustainable intervention thresholds is crucial for effective public health policy.

Purpose of the Study:

  • To introduce a method for computing sustainable thresholds for controlled cooperative models.
  • To provide a framework for understanding trade-offs between different control constraints.
  • To inform efficient decision-making in disease outbreak management.

Main Methods:

  • Utilizing systems of ordinary differential equations to model disease dynamics.
  • Defining sustainable thresholds as constraints achievable under admissible control strategies.
  • Analyzing the impact of initial states on the set of sustainable thresholds.

Main Results:

  • The method computes a set of sustainable thresholds, offering insights into achievable control levels.
  • Demonstrated the trade-offs between budget, human infections, and vector populations.
  • Applied the method to the 2013 dengue outbreak in Cali, Colombia.

Conclusions:

  • The developed method offers a valuable tool for optimizing disease control interventions.
  • Sustainable thresholds provide crucial information for cost-effective public health planning.
  • The approach has significant potential for real-world applications in managing epidemics.