Assessment of MRI issues at 1.5 T for the Temperature Logger Implant

The Temperature Logger Implant is a newly developed device that is capable of providing data for animal studies on thermoregulatory function, hibernation, hypothermia, and general health. During research, it may be necessary to conduct a magnetic resonance imaging (MRI) examination on an animal with this device implanted to assess anatomical changes or other conditions. Notably, this new device was specially designed to be unaffected by the electromagnetic fields used for MRI. Therefore, to verify that there would be no problems related to MRI, the purpose of this investigation was to evaluate MRI-related issues for the Temperature Logger Implant.

Tests were performed on the Temperature Logger Implant using well-accepted techniques to evaluate magnetic field interactions (translational attraction and torque, 1.5 T), MRI-related heating (whole body averaged specific absorption rate, 2.9 W/kg), artifacts (T1-weighted, spin echo and gradient echo pulse sequences), and functional changes related to exposure to eight different imaging conditions.

Magnetic field interactions were relatively low (deflection angle 4°, no torque) and heating was minor (highest temperature rise, > 1.1 °C) indicating that these factors will not pose a hazard to an animal. The largest artifact (gradient echo pulse sequence) extended 10 mm from the size and shape of the Temperature Logger Implant. Exposure to the eight different conditions at 1.5 T/ 64 MHz did not alter or damage the operational aspects of the device.

The findings demonstrated that MRI can be performed safely on an animal with this new Temperature Logger Implant and, thus, this device is deemed "MR Conditional" (i.e., using current labeling terminology), according to the conditions used in this investigation.