Related Experiment Video
Updated: Feb 10, 2026

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
Published on: January 22, 2015
Preparation, characterization, and functional evaluation of proanthocyanidin-chitosan conjugate
Yingjun Jing1, Jianghao Huang1, Xueqing Yu1
1School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.
Abstract:
In this study, chitosan (CS) was conjugated with proanthocyanidin (PA) by a free radical grafting reaction. The successful synthesis of PA-CS conjugate was confirmed by Fourier transform infrared spectroscopy and proton nuclear magnetic resonance. The optimal molar ratio of PA to CS repeat unit for the preparation of PA-CS was 0.13:1, which led to a high PA content of 381.76 mg PAE/g in PA-CS. The antioxidant assays demonstrated that PA-CS had much stronger radical scavenging activity and reducing power than the native CS. Especially, the half-inhibition concentrations of PA-CS against DPPH and ABTS radicals were only 6.2 μg/mL and 5.9 μg/mL, respectively. In addition, PA-CS showed an alteration in antibacterial activity compared with CS, and the alteration varied with bacterial strain.
More Related Videos
15:03Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection
Published on: June 16, 2020
08:05Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
Published on: September 29, 2017
Related Concept Videos
Conjugated Proteins
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
Conjugated Proteins
Conjugation
Mechanism of Conjugation
Relative Strengths of Conjugate Acid-Base Pairs
Structure of Conjugated Dienes
Conjugated dienes are compounds characterized by the presence of alternating double and single bonds. In a conjugated system like 1,3-butadiene, the unhybridized 2p orbital on each carbon overlaps continuously, allowing the π electrons to be delocalized across the entire molecule. In contrast, this type of overlap does not occur in cumulated and isolated dienes, such as 2,3-pentadiene and 1,4-pentadiene, respectively. Instead, the π electrons remain localized between the double...