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Related Concept Videos

Hypersensitivities01:30

Hypersensitivities

7.7K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
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GPCR Desensitization01:12

GPCR Desensitization

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G protein-coupled receptor (GPCR) signaling plays a crucial role in cell functioning. GPCR desensitization is an equally essential process. It allows cells to respond to changing environments and regain sensitivity to new stimuli while preventing unnecessary stimulation when no longer needed. Prolonged exposure to stimuli leads to GPCR desensitization. It involves blocking the receptors from binding and activating additional G proteins. This inhibits activation of downstream effectors, thereby...
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Desensitization and Tachyphylaxis01:20

Desensitization and Tachyphylaxis

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Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
3.1K
Decreasing Function01:27

Decreasing Function

305
A decreasing function describes a relationship where the output consistently declines as the input increases. This means that for any two input values, if one is greater than the other, the corresponding output is smaller. Mathematically, a function f is decreasing on an interval I if for every x1 < x2​ in I, f (x1) > f (x2). This type of behavior is visually identified on a graph that slopes downward from left to right.The nature of a function can be analyzed by calculating...
305
Tooth Anatomy01:21

Tooth Anatomy

2.2K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.2K
Decreased Body Temperature01:29

Decreased Body Temperature

1.1K
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Important uncertainty about the impact of orthodontic treatment with fixed appliances on oral health-related quality of life.

Journal of the American Dental Association (1939)·2019
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Patients who are obese probably have worse peri-implant outcomes than those who are not, but there is not sufficient evidence that the implant survival is different.

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Small trial shows high rates of endodontic treatment success with iodoform or calcium hydroxide paste in primary teeth after 1 year.

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Self-management interventions may be more effective than usual care for treating patients with chronic orofacial pain.

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Very low-quality evidence suggests that there are no differences in implant failure and bone loss between machined and rough surface dental implants in patients with periodontitis.

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Systematic review confirms that lymph node compromise is associated with the prognosis of oral squamous cell carcinoma.

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Related Experiment Video

Updated: Feb 10, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
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Desensitizing gel reduces the risk of experiencing dentin hypersensitivity and results in a small decrease in

Romina Brignardello-Petersen

    Journal of the American Dental Association (1939)
    |May 27, 2018
    PubMed
    Summary

    No abstract available in PubMed .

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