The factors associated with successful early enteral feeding in gastroschisis

Theerayuth Pratheeppanyapat1, Kanokkan Tepmalai1, Jesda Singhavejsakul1

  • 1Division of Pediatric Surgery, Department of Surgery, Chiang Mai University Hospital, 110 Intavaroros Road, Muang Chiang Mai District, Chiang Mai, 50200, Thailand.

Insights

Successful early enteral feeding in gastroschisis is linked to factors like female sex, later gestational age, and prompt surgery. Modifiable factors include early surgery, extubation, and feeding initiation to improve outcomes.

Area of Science:

  • Pediatric Surgery
  • Neonatal Care
  • Congenital Abnormalities

Background:

  • Gastroschisis is a common congenital abdominal wall defect.
  • Delayed bowel function recovery is frequent due to midgut exposure to amniotic fluid.

Purpose of the Study:

  • Identify factors associated with successful early enteral feeding in gastroschisis.
  • Develop improved treatment guidelines for gastroschisis management.

Main Methods:

  • Retrospective cohort study of 105 gastroschisis patients (2006-2015).
  • Exclusion criteria: incomplete data and mortality.
  • Successful early enteral feeding defined as full feeding within 21 days of life.

Main Results:

  • 53% (n=56) achieved successful early feeding.
  • Factors associated with success: female sex (RR=1.38), gestational age >36 weeks (RR=1.23), surgery <10h (RR=1.15), extubation <4 days (RR=1.39), feeding start <10 days (RR=35.69).

Conclusions:

  • Several factors influence successful early enteral feeding in gastroschisis.
  • Modifiable factors include surgery within 10 hours, extubation within 4 days, and feeding initiation before 10 days.
  • Findings can guide gastroschisis management for better outcomes.
Abstract

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