Related Experiment Video
Updated: Feb 10, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
Uterine transposition after radical trachelectomy
Glauco Baiocchi1, Henrique Mantoan1, Michael Jenwei Chen2
1Department of Gynecologic Oncology, AC Camargo Cancer Center, Sao Paulo, Brazil.
Objective:
To report the first uterine transposition for fertility sparing in cervical cancer.
Methods:
We report a 33-year-old woman with stage Ib1 cervical cancer (b2 cm in size) who had a radical trachelectomy that, after the definitive pathological report, fulfilled the criteria for adjuvant radiotherapy.
Results:
The patient had eggs retrieval and received gosereline 10.8 mg before surgery. The uterine corpus and ovaries were detached from the previous vaginal anastomosis, laparoscopically mobilized, and sutured in the right upper abdominal wall with non-absorbable transparietal suture. The adjuvant external beam radiotherapy (45 Gy) was delivered in the pelvis. One week after, the uterus and ovaries were repositioned and sutured in the vagina. The patient had hospital discharged in the 2° post-operative day and no early complications. After 6 months of follow-up the patient has regular menses and no evidence of recurrence.
Conclusions:
Uterine transposition is feasible after radical trachelectomy in selected patients who still desire to preserve fertility. However, further studies that address its effectiveness and safety are required.
Related Concept Videos
Overview of Transposition and Recombination
Uterine Tubes
Radical Reactivity: Nucleophilic Radicals
Radicals
Radical Reactivity: Electrophilic Radicals
Radical Autoxidation

