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Updated: Feb 10, 2026

Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma
Published on: July 6, 2022
Total Circulating Microparticle Levels After Laparoscopic Surgical Treatment for Endometrioma: A Pilot, Prospective,
Jordina Munrós1, Maria-Angeles Martínez-Zamora1, Dolors Tàssies2
1Department of Gynecology, Clinical Institute of Gynecology, Obstetrics, and Neonatology, Hospital Clinic of Barcelona, Faculty of Medicine, University of Barcelona, Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Study Objective:
To evaluate serial generation of microparticles (MPs) after laparoscopic stripping or CO2 laser vaporization in the surgical treatment of patients with ovarian endometrioma (OE).
Design:
A prospective, randomized, blinded, pilot study (Canadian Task Force classification I).
Setting:
Tertiary care university hospital from December 2014 to July 2016.
Patients:
Thirty women with unilateral OE undergoing laparoscopic surgery.
Intervention:
Patients were randomly selected to undergo either CO2 laser vaporization (L group) or laparoscopic stripping (S group) of OE.
Measurements And Main Results:
Blood samples were collected before surgery and at 2 hours, 24 hours, 1 month, and 3 months after surgery. An MP generation curve after OE surgery was created. MP generation was greater in the S group than in the L group at all time points evaluated. The MP generation curve showed a significantly higher area under the curve after excisional surgery (p <.05).
Conclusion:
The higher MP levels in the S group suggest an increased inflammation and procoagulant response after this procedure.
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