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Novel markers to track oxidative polysorbate degradation in pharmaceutical formulations

Sanket Dahotre1, Anthony Tomlinson1, Baiwei Lin2

  • 1Late Stage Pharmaceutical Development, Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.

Journal of Pharmaceutical and Biomedical Analysis
|May 28, 2018
PubMed

Keywords:
2,4-DinitrophenylhydrazineBiopharmaceutical formulationsFatty acid estersOxidative degradationPolysorbate 20Reverse phase ultra high performance liquid chromatography

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