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Author Spotlight: Advancements and Challenges in Machine Perfusion for Liver Transplantation
Published on: June 14, 2024
Cardiac diseases among liver transplant candidates
Marina Gitman1, Megan Albertz2, Ramona Nicolau-Raducu3
1Department of Anesthesiology, University of Illinois Hospital, Chicago, IL, USA.
Insights
Liver transplant (LT) candidates often have comorbidities. Cardiovascular disease poses risks, necessitating a structured approach for cardiac assessment and perioperative management in these patients.
Area of Science:
- Cardiology
- Transplant Surgery
- Internal Medicine
Background:
- Improved early survival in liver transplant (LT) recipients enables selection of candidates with complex comorbidities.
- Cardiovascular disease is a significant factor in post-LT complications and mortality.
- Current preoperative cardiac assessment guidelines for LT candidates are limited, particularly outside of pulmonary hypertension.
Purpose of the Study:
- To identify common causes of cardiac disease in the liver transplant population.
- To review diagnostic techniques for cardiac conditions in LT candidates.
- To describe perioperative management strategies for cardiac disease in LT recipients.
Main Methods:
- Comprehensive literature search for studies on cardiac disease in liver transplant recipients.
- Analysis of identified causes, diagnostic modalities, and management strategies.
- Development of a recommended algorithm for preoperative cardiac evaluation.
Main Results:
- Cardiovascular disease is a prevalent comorbidity impacting liver transplant outcomes.
- Various diagnostic tools are available for assessing cardiac function and disease.
- Perioperative management requires careful consideration of cardiac status.
Conclusions:
- A systematic preoperative cardiac work-up is crucial for liver transplant candidates.
- The proposed algorithm aims to standardize cardiac assessment, improving patient selection and outcomes.
- Further research may refine guidelines for managing cardiovascular disease in this population.
Abstract:
Improvements in early survival after liver transplant (LT) have allowed for the selection of LT candidates with multiple comorbidities. Cardiovascular disease is a major contributor to post-LT complications. We performed a literature search to identify the causes of cardiac disease in the LT population and to describe techniques for diagnosis and perioperative management. As no definite guidelines for preoperative assessment (except for pulmonary heart disease) are currently available, we recommend an algorithm for preoperative cardiac work-up.
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