Related Experiment Video
Updated: Feb 10, 2026
05:19
Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
10.7K
[Overweight and gastro-oesophageal reflux disease]
Melina Capello1, Anne Lund Karup, Peter Rask
1nielsenm@post7.tele.dk.
Ugeskrift for Laeger
|May 29, 2018
Summary
Obesity and gastro-oesophageal reflux disease (GERD) are increasing. Weight loss is key for GERD treatment, with gastric bypass surgery recommended for obese patients with GERD.
Area of Science:
- Gastroenterology and Bariatric Surgery
Background:
- Rising obesity rates correlate with increased gastro-oesophageal reflux disease (GERD) prevalence.
- Obesity presents unique challenges for GERD management and surgical interventions.
Purpose of the Study:
- To explore the intricate relationship between overweight/obesity and GERD.
- To review and outline effective treatment strategies for GERD in the context of obesity.
Main Methods:
- Literature review of studies examining obesity, GERD, and surgical outcomes.
- Analysis of treatment guidelines and clinical recommendations.
Main Results:
- Weight loss is a critical component in managing GERD.
- While fundoplication is suitable for normal-weight individuals, gastric bypass surgery is indicated for patients with obesity and GERD due to increased complication risks with higher BMI.
Conclusions:
- Gastric bypass surgery is the preferred surgical approach for managing GERD in patients with obesity.
- Tailoring treatment based on BMI is essential for effective GERD management.
More Related Videos
Related Concept Videos
01:29Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
1.7K
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
1.7K
01:29Gastroesophageal Reflux Disease II: Clinical Features and Management
970
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
970
01:30Inflammatory Bowel Disease II: Crohn's Disease
1.2K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.2K
01:25Immunodeficiency Diseases
2.5K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
2.5K
01:24Parkinson's Disease: Treatment
1.2K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.2K
01:22Alzheimer's Disease: Treatment
968
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
968