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Updated: Feb 10, 2026

Fabricating Cotton Analytical Devices
Published on: August 30, 2016
Figuration of Zr-based MOF@cotton fabric composite for potential kidney application
Reda M Abdelhameed1, Mohamed Rehan2, Hossam E Emam2
1Applied Organic Chemistry Department, National Research Centre, Scopus Affiliation ID 60014618, 33 EL Buhouth St., Dokki, Giza, 12622, Egypt.
Abstract:
Hemodialysis is one of the earliest artificial kidney systems, which removes uremic toxins through using a semipermeable porous membrane. Current report focuses on designation of metal organic framework (MOF) based zirconium@cotton fabric composite and its application in kidney dialysis. UiO-66-(COOH)2 as MOF material was directly grown within cotton fabric. Fabric was firstly reacted with benzene tetra carboxylic acid forming ester and then Zr was interacted with the free carboxylic groups in the formed ester to produce UiO-66-(COOH)2@cotton fabric composite. The obtained composite was characterized by using electron microscope, X-ray diffraction, infrared spectroscopy and colorimetric data. After modification with MOF, fabric was acquired yellowish color. The prepared composite was used in potential kidney application through studying the removal of creatinine from mimic blood. The maximum adsorption capacity of creatinine was 113.6 and 192.3-212.8 mg/g for pristine fabric and UiO-66-(COOH)2@fabric composite, respectively. From adsorption data, creatinine adsorption onto composite was followed to pseudo-second order kinetic model and Langmuir isotherm profile. After three regeneration cycles, the applied composite still achieved substantial adsorption capacity by removing of 82% from creatinine. UiO-66-(COOH)2@cotton could be considered as successful adsorbent capable of removing creatinine from blood with good reusability, which can be applied in kidney dialysis.
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