Photoleukocoria with smartphone photographs

A 3-year-old boy was referred with suspected leukocoria in the right eye, detected in all smartphone photographs taken by his parents. His medical and family history was unremarkable. The visual acuity was 20/20 in both eyes. Eye examination revealed full motility and normal pupils. The ocular fundi and ultrasonography appeared normal. The child was looking to the left side in his photographs, away from the camera, and illuminating the nasal retina. In this circumstance, the optic nerve head acts as a diffuse reflector, reflecting the light out of the eye through the pupil. In the case of normal clinical findings in a child presenting leukocoria in smartphone photographs (photoleukocoria), the ophthalmologist should suspect the possibility of the described phenomenon avoiding other studies.