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Updated: Feb 10, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
Published on: February 27, 2011
Magnetic resonance imaging findings in newly diagnosed epileptic children
Mehmet Alp Dirik1, Burcin Sanlidag2
1Mehmet Alp Dirik, MD. Radiologist, Department of Radioloy, Dr. Suat Gunsel University, Faculty of Medicine, Kyrenia, North Cyprus.
Insights
Brain Magnetic Resonance Imaging (MRI) revealed structural abnormalities in nearly half of newly diagnosed epileptic children. Common findings included encephalomalacia, hydrocephaly, and brain atrophy, indicating a high prevalence of lesions in pediatric epilepsy.
Area of Science:
- Pediatric Neurology
- Neuroimaging
- Epileptology
Background:
- Epilepsy is a common chronic neurologic disorder affecting 0.5-1% of children.
- Structural abnormalities are frequently implicated in the etiology of childhood epilepsy.
Purpose of the Study:
- To determine the prevalence and types of structural abnormalities in children diagnosed with epilepsy.
- To analyze Magnetic Resonance Imaging (MRI) findings in a cohort of pediatric epilepsy patients.
Main Methods:
- Retrospective analysis of MRI scans from epileptic children aged 1-18 years.
- Inclusion criteria: MRI performed within 6 months of epilepsy diagnosis.
- Data collected from Near East University and Dr. Suat Gunsel University between October 2011 and June 2017.
Main Results:
- Out of 220 children, 89 (45.45%) exhibited at least one structural abnormality on MRI.
- The most frequent lesions observed were encephalomalacia (5.90%), hydrocephaly (5.45%), and brain atrophy (4.55%).
- Sixty-nine patients (31.06%) had a single abnormality, while 20 (9.09%) had two or more lesions.
Conclusions:
- A significant proportion of newly diagnosed epileptic children present with structural abnormalities on MRI.
- The high prevalence may relate to the inclusion of new-onset epilepsy cases.
- Concomitant lesions were noted in 9.09% of patients, with secondary lesions associated with corpus callosum abnormalities, atrophy, encephalomalacia, and hydrocephaly.
Objectives:
Epilepsy is one of the most common chronic neurologic disorders in childhood and it affects 0.5-1% of children. The purpose of the study was to determine the prevalence and types of structural abnormalities in the epileptic children.
Methods:
The study was performed in Near East University and Dr. Suat Gunsel University in North Cyprus. It was conducted at pediatric neurology outpatient clinic of the hospital. The records of 1 to 18 years old epileptic children in whom Magnetic Resonance Imaging (MRI) performed within 6 months after diagnosis were enrolled to the study between the dates of October 2011 and June 2017.
Results:
Among 220 children; 131 (59.55%) had no abnormality and 89 (45.45%) had at least one abnormality in the MRI. Most commonly documented lesions were generally encephalomalacia, hydrocephaly and brain atrophy with a percent of 5.90 (13 cases), 5.45 (12 cases) and 4.55 (10 cases) respectively. Sixty nine (31.06%) of the patients had one abnormality whereas 20 (9.09%) had two or more lesion.
Conclusion:
Abnormality in MRI examination in newly diagnosed epileptic children was high. These high rates may be due to enrollment of children with new emerging epilepsy on a chronical neurologic disorder. Additionally 20 (9.09%) of patients had a concomitant lesion. Secondary lesions were detected in cases with corpus callosum abnormality, atrophy, encephalomalacia and hydrocephaly. Primarily formed lesions are unknown; further studies are needed to confirm these findings.
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