Magnetic resonance imaging findings in newly diagnosed epileptic children

Mehmet Alp Dirik1, Burcin Sanlidag2

  • 1Mehmet Alp Dirik, MD. Radiologist, Department of Radioloy, Dr. Suat Gunsel University, Faculty of Medicine, Kyrenia, North Cyprus.

Insights

Brain Magnetic Resonance Imaging (MRI) revealed structural abnormalities in nearly half of newly diagnosed epileptic children. Common findings included encephalomalacia, hydrocephaly, and brain atrophy, indicating a high prevalence of lesions in pediatric epilepsy.

Area of Science:

  • Pediatric Neurology
  • Neuroimaging
  • Epileptology

Background:

  • Epilepsy is a common chronic neurologic disorder affecting 0.5-1% of children.
  • Structural abnormalities are frequently implicated in the etiology of childhood epilepsy.

Purpose of the Study:

  • To determine the prevalence and types of structural abnormalities in children diagnosed with epilepsy.
  • To analyze Magnetic Resonance Imaging (MRI) findings in a cohort of pediatric epilepsy patients.

Main Methods:

  • Retrospective analysis of MRI scans from epileptic children aged 1-18 years.
  • Inclusion criteria: MRI performed within 6 months of epilepsy diagnosis.
  • Data collected from Near East University and Dr. Suat Gunsel University between October 2011 and June 2017.

Main Results:

  • Out of 220 children, 89 (45.45%) exhibited at least one structural abnormality on MRI.
  • The most frequent lesions observed were encephalomalacia (5.90%), hydrocephaly (5.45%), and brain atrophy (4.55%).
  • Sixty-nine patients (31.06%) had a single abnormality, while 20 (9.09%) had two or more lesions.

Conclusions:

  • A significant proportion of newly diagnosed epileptic children present with structural abnormalities on MRI.
  • The high prevalence may relate to the inclusion of new-onset epilepsy cases.
  • Concomitant lesions were noted in 9.09% of patients, with secondary lesions associated with corpus callosum abnormalities, atrophy, encephalomalacia, and hydrocephaly.
Abstract

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