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MRI manifestations of hepatic perfusion disorders

Qing-Yong Cao1, Zhi-Meng Zou1, Qi Wang1

  • 1Department of Radiology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.

Experimental and Therapeutic Medicine
|May 29, 2018
PubMed

Insights

Magnetic resonance imaging (MRI) accurately diagnoses hepatic perfusion disorders (HPD) in liver diseases. Hepatocellular carcinoma is a major cause of HPD, which MRI can classify into distinct types.

Area of Science:

  • Radiology
  • Hepatology
  • Medical Imaging

Background:

  • Hepatic perfusion disorders (HPD) are complex conditions affecting liver blood flow.
  • Understanding the pathogenetic mechanisms of HPD is crucial for diagnosing and managing liver diseases.

Purpose of the Study:

  • To analyze MRI findings in patients with HPD and liver diseases.
  • To assess pathogenetic mechanisms of HPD, including association with arterioportal shunts.
  • To classify HPD based on MRI characteristics.

Main Methods:

  • Retrospective analysis of MRI results from 35 patients with HPD.
  • Evaluation of causes of HPD, focusing on arterioportal shunts.
  • Classification of patients based on MRI findings (T2WI, T1WI, diffusion-weighted images, enhanced scanning).

Main Results:

  • Hepatocellular carcinoma was identified in 74.3% of HPD patients.
  • HPD showed isointensity on diffusion-weighted images, with specific signal characteristics on enhanced scans (arterial, portal, delayed phases).
  • MRI identified four types of HPD: diffuse, lobe/segment, wedge, and platy.

Conclusions:

  • MRI is an accurate diagnostic tool for HPD in liver diseases.
  • HPD can be classified into distinct types based on MRI findings.
  • The HPD phenomenon may indicate an underlying liver abnormality.
Keywords:
disordershepaticmagnetic resonance imagingperfusion

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