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Updated: Aug 19, 2026

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
Published on: November 19, 2008
Perinatal hypoxic-ischaemic syndrome. Diagnostic and prognostic value of computed tomography
E Guardia1, X Demestre, F Raspall
1Seccion de Neuroradiologia, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Abstract:
Sixty-two full-term neonates with hypoxic-ischaemic encephalopathy were studied. Computed tomography (CT) was performed during the first week of life and the clinical and radiologic findings were correlated. In 57 cases (92%) CT was abnormal. Subarachnoid haemorrhage (SAH) was present in 53 cases, oedema in 23 cases and other lesions in 7 cases. Twenty-two cases had associated SAH and oedema. It was concluded that SAH and/or oedema has a good prognosis. When neurologic involvement is severe and CT shows signs of necrosis, the prognosis is less favourable.
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