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Related Experiment Video

Updated: Feb 10, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
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Essential tremor and depression.

Sana Aslam1, Nan Zhang2, Charles H Adler2

  • 1Barrow Neurological Institute, Phoenix, AZ.

Movement Disorders Clinical Practice
|May 29, 2018
PubMed
Summary
This summary is machine-generated.

Essential tremor (ET) patients do not show higher rates of depression compared to controls. Depressive symptoms in ET are not linked to tremor severity, duration, or age of onset.

Keywords:
cognitivedepressionessential tremortremor

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Area of Science:

  • Neurology
  • Psychiatry

Background:

  • Essential tremor (ET) is a common neurological disorder.
  • The prevalence of depression and neuropsychiatric disorders in ET patients is not well-established.

Purpose of the Study:

  • To investigate the association between essential tremor and depressive symptoms.
  • To explore the relationship between tremor characteristics and depression in ET patients.

Main Methods:

  • A comparative study involving 104 ET subjects and 481 non-ET controls from the Arizona Study of Aging and Neurodegenerative Disorders.
  • Analysis of baseline depression scales and the Neuropsychiatric Inventory (NPI).
  • Subgroup analyses within the ET group based on tremor severity, duration, and age of onset.

Main Results:

  • No significant differences in depression scales or NPI scores were found between ET and non-ET groups.
  • No significant differences in depressive symptoms were observed within the ET group based on tremor severity, duration, or age of onset.
  • Subjectively distressing tremor did not correlate with higher depressive symptoms.

Conclusions:

  • Depressive symptoms are not more prevalent in individuals with essential tremor compared to controls.
  • Tremor severity, duration, or age of onset do not correlate with depressive symptoms in ET patients.