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Organic Arsenicals as Functional Motifs in Polymer and Biomaterials Science
Joji Tanaka1, Thomas P Davis1,2, Paul Wilson1,2
1Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.
Abstract:
Arsenic (As) exhibits diverse (bio)chemical reactivity and biological activity depending upon its oxidation state. However, this distinctive reactivity has been largely overlooked across many fields owing to concerns regarding the toxicity of arsenic. Recently, a clinical renaissance in the use of arsenicals, including organic arsenicals that are known to be less toxic than inorganic arsenicals, alludes to the possibility of broader acceptance and application in the field of polymer and biomaterials science. Here, current examples of polymeric/macromolecular arsenicals are reported to stimulate interest and highlight their potential as a novel platform for functional, responsive, and bioactive materials.
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