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Updated: Feb 10, 2026

Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues
Published on: March 31, 2016
[Research progress of miRNA regulation in differentiation of adipose-derived stem cells]
Lanting Zhou1, Yanting Feng2, Jingxing Dai2
1Medical College, Hubei University of Arts and Science, Xiangyang Hubei, 441053, P.R.China;Department of Anatomy, Southern Medical University, Guangzhou Guangdong, 510515, P.R.China.
Objective:
To review the research progress of miRNA regulation in the differentiation of adipose-derived stem cells (ADSCs).
Methods:
The recent literature associated with miRNAs and differentiation of ADSCs was reviewed. The regulatory mechanism was analyzed in detail and summarized.
Results:
The results indicate that the expression of miRNAs changes during differentiation of ADSCs. In addition, miRNAs regulate the differentiation of ADSCs into adipocytes, osteoblasts, chondrocytes, neurons, and hepatocytes by regulating the signaling pathways involved in cell differentiation.
Conclusion:
Through controlling the differentiation of ADSCs by miRNAs, the suitable seed cell for tissue engineering can be established. The review will provide a theoretical basis for molecular targeted therapy and stem cell therapy in clinic.
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