Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

1.5K
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
1.5K
Lung Capacity01:47

Lung Capacity

56.4K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.4K
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

619
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
619
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

904
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
904
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

693
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
693
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

745
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
745

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is chest pain in achalasia always due to spasm?

Revista espanola de enfermedades digestivas·2025
Same author

Esophageal biomechanics assessed by impedance planimetry (EndoFLIPTM) in healthy subjects and in patients with eosinophilic esophagitis. Normality values.

Revista espanola de enfermedades digestivas·2023
Same author

Risk of COVID-19 transmission in esophageal, anorectal manometry and 24-hour impedance-pH monitoring.

Revista espanola de enfermedades digestivas·2021
Same author

Gastro-esophageal reflux disease: limits of medical treatment and surgical indications.

Revista espanola de enfermedades digestivas·2021
Same author

Achalasia. New concepts.

Medicina clinica·2017
Same author

Practical aspects of high resolution esophageal manometry.

Revista espanola de enfermedades digestivas·2016

Related Experiment Video

Updated: Feb 10, 2026

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

782

Lung transplantation and esophageal dysfunction.

Antonio Ruiz de León San Juan1

  • 1Aparato Digestivo, Hospital Universitario Cínico San Carlos, España.

Revista Espanola De Enfermedades Digestivas
|May 30, 2018
PubMed
Summary
This summary is machine-generated.

Lung transplant outcomes are poor due to rejection and bronchiolitis. Esophagogastric issues like GER and dysmotility are prevalent in patients, worsening post-transplant and impacting viability.

More Related Videos

Orthotopic Left Lung Transplantation in Rats
08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

757
ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
05:57

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection

Published on: February 10, 2017

8.9K

Related Experiment Videos

Last Updated: Feb 10, 2026

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

782
Orthotopic Left Lung Transplantation in Rats
08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

757
ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
05:57

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection

Published on: February 10, 2017

8.9K

Area of Science:

  • Gastroenterology and Pulmonology
  • Transplant Medicine
  • Diagnostic Technology

Background:

  • Lung transplantation has poorer outcomes compared to other organ transplants, primarily due to acute rejection and bronchiolitis obliterans.
  • Esophagogastric diseases, including gastroesophageal reflux (GER), esophageal dysmotility, and gastroparesis, are highly prevalent in patients with end-stage pulmonary disease awaiting lung transplants.
  • These conditions often worsen after transplantation, potentially compromising the viability of the transplanted lung allograft.

Discussion:

  • The study highlights the significant impact of esophagogastric disorders on lung transplant outcomes.
  • It suggests that these conditions, often overlooked, play a crucial role alongside traditional concerns like rejection.
  • The interplay between GER, dysmotility, and transplant viability requires further investigation.

Key Insights:

  • Gastroesophageal reflux (GER), esophageal dysmotility, and gastroparesis are common in lung transplant candidates and recipients.
  • These prevalent GI conditions can negatively affect lung allograft survival.
  • Advanced diagnostic tools like high-resolution impedance manometry and pH-metry offer new insights into these issues.

Outlook:

  • Future research should focus on integrating GI assessments into pre-transplant evaluations.
  • Therapeutic strategies targeting GER and dysmotility may improve lung transplant outcomes.
  • Developing standardized protocols for managing esophagogastric disease in lung transplant recipients is essential.