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Updated: Feb 10, 2026

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
Published on: June 28, 2013
Multi-Target Antitubercular Drugs
Jessika de Oliveira Viana1, Hamilton Mitsugu Ishiki2, Marcus Tullius Scotti1
1Cheminformatics Laboratory, Postgraduate Program in Natural Products and Synthetic Bioactive, Federal University of Paraiba, Campus I, 58051-900, Joao Pessoa-PB, Brazil.
Abstract:
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has high levels of mortality worldwide and has already gained resistance to first- and second-line drugs. The study by new chemical entities with promising activities becomes paramount to broaden the therapeutic strategies in the cure of the patients affected with this disease. In this context, in this review we report the discovery of 3 classes of compounds that can simultaneously interact with more than one target of Mycobacterium tuberculosis.
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