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Updated: Feb 10, 2026

Isolation of Primary Mouse Retinal Pigmented Epithelium Cells
Published on: November 4, 2022
Detachment of retinal pigment epithelium in retinopathy due to malaria
P Rocha Cabrera1, I Rodríguez Talavera1, M J Losada Castillo1
1Servicio de Oftalmología, Hospital San Juan de Dios, Tenerife, España.
Case Report:
A 45-year-old man was diagnosed with malaria with neurological involvement. Two months later he referred metamorphopsia in the left eye. Malarial retinopathy was observed in the fundus examination. The Optic Coherence Tomography (OCT) of the macula showed parafoveal pigment epithelium detachment (DEP). Specific anti-malarial treatment was initiated, with the disappearance of the retinopathy being observed.
Discussion:
Plasmodium falciparum is responsible for the retinopathy in neurological malaria. A funduscopic examination and macular OCT should be performed in these patients, as it is associated with a higher mortality when there is a retinal involvement.
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