Related Experiment Video
Updated: Feb 10, 2026
DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
Published on: July 15, 2011
Leprosy manifesting with type 2 leprae reaction in a patient presenting with chronic fever: A case report
Fivzia Farooq Herekar1, Hiba Ashraf1, Naseem Salahuddin1
1The Indus Hospital, Karachi.
Abstract:
Leprosy is a chronic granulomatous disease involving the skin and nerves, leading to a debilitating condition. Leprosy has been controlled in most parts of the world; therefore physicians are not very well versed in the recognition, management and assessment of this disease. The protean manifestations of leprosy often lead to delays in diagnosis and increase the morbidity. We present a case of a 33-year-old male with fever, lymphadenopathy, nodular skin lesions, uveitis and arthritis. Lymphnode, bonemarrow and skin biopsy revealed 3+ AFB smear with negative AFB cultures, leading to the diagnosis of leprosy. The course of illness was complicated by flare of Erythema Nodosum Leprosum (ENL).
Insights
Physicians may overlook leprosy due to its rarity, leading to delayed diagnosis. This case highlights the varied symptoms of leprosy and its complication, Erythema Nodosum Leprosum (ENL), emphasizing the need for awareness.
Area of Science:
- Medical Microbiology
- Immunology
- Dermatology
Background:
- Leprosy is a chronic granulomatous disease affecting skin and nerves.
- Physician unfamiliarity with leprosy's diverse presentations can cause diagnostic delays and increased morbidity.
- The disease has been largely controlled globally, reducing clinical exposure.
Related Concept Videos
01:25Types of Fever
Here are the different types of fever:
01:25Types of Reports I: Hands-off Report
Following are the key components and categories of hand-off reports:
Purpose and Process:
01:24Chronic Kidney Disease II: Clinical Manifestations
01:21Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
01:26Types of Reports III: Telephone and Verbal Reports
Here's an overview of each type:
Telephone Orders
02:14SN2 Reaction: Kinetics
In a chemical reaction, a relationship exists between the concentration of reactants and the rate at which the reaction proceeds. The study to measure this relationship is known as the kinetics of a chemical reaction. Kinetic studies are used to deduce the rate law of a chemical reaction, which provides information about the species involved during the transition state of the rate-determining step. Thus, kinetic studies help to derive the mechanism of a...