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Updated: Feb 10, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
Spinal anesthesia for surgery longer than 60 min in infants: experience from the first 2 years of a spinal anesthesia
Mehdi Trifa1,2, Dmitry Tumin3, Emmett E Whitaker3,4
1Department of Anesthesiology, Pain Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. mehditrifa@gmail.com.
Insights
Spinal anesthesia (SA) is a successful alternative to general anesthesia (GA) in infants for surgeries up to 100 minutes. This study found SA effective in 89% of pediatric cases, offering a safer option for young children.
Area of Science:
- Pediatric Anesthesiology
- Regional Anesthesia Techniques
- Neurodevelopmental Outcomes
Background:
- General anesthesia (GA) may negatively impact neurocognitive development in infants.
- Spinal anesthesia (SA) is an emerging alternative to GA for pediatric procedures.
- SA's duration has been a limitation for longer surgeries.
Purpose of the Study:
- To evaluate the success rate of spinal anesthesia (SA) for pediatric surgical procedures exceeding 60 minutes.
- To determine if SA can provide adequate anesthesia duration for extended surgeries in children up to 3 years old.
- To assess SA as a viable alternative to GA, minimizing potential neurocognitive risks.
Main Methods:
- Retrospective review of pediatric patients (up to 3 years) undergoing surgery >60 minutes under SA.
- SA involved bupivacaine 0.5% (1 mg/kg, max 7 mg) with clonidine and epinephrine.
- Primary outcome: successful SA without conversion to GA; secondary: need for sedation.
Main Results:
- 35 male infants (mean age 7 months, weight 8 kg) met inclusion criteria.
- Average surgical duration was 71 minutes (range 60-111 minutes).
- SA success rate was 89% (31/35), with failure rarely due to insufficient duration. Six patients required additional sedation.
Conclusions:
- Spinal anesthesia (SA) demonstrates high success rates (89%) for pediatric surgeries lasting up to 100 minutes.
- SA is a viable alternative to GA in children for appropriate surgical procedures.
- Further research can explore optimizing SA for extended durations and diverse pediatric populations.
Purpose:
Spinal anesthesia (SA) is being increasingly used in infants to avoid the potential negative neurocognitive effects of general anesthesia (GA). However, SA has been reported to provide a relatively short duration of surgical anesthesia.
Methods:
We retrospectively reviewed SA cases for surgical procedures lasting more than 60 min in children up to 3 years old. All patients received bupivacaine 0.5% (1 mg/kg up to 7 mg) with clonidine 1 µg/kg ± epinephrine. The primary outcome was success of SA without subsequent conversion to GA.
Results:
Thirty-five patients met inclusion criteria (all males, age 7 ± 5 months, weight 8 ± 2 kg). Procedures included male genital, groin and multiple site surgeries. Average surgical duration was 71 ± 12 min (range 60-111 min). SA was successful in 31 of 35 patients (89%; 95% confidence interval 78, 99%). The cause of failure was rarely due to the duration of surgery (1 of 4 patients). Six patients with successful SA required sedation with dexmedetomidine ± fentanyl. Differences in procedure duration and patient characteristics were not statistically significant between successful and failed SA.
Conclusions:
SA is a highly successful technique and may offer an alternative to GA in children undergoing appropriate surgery expected to last as long as 60-100 min.
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