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Updated: Feb 10, 2026

High-Resolution C. elegans Imaging Across All Larval Stages
Published on: May 23, 2025
Correction: Long-term C. elegans immobilization enables high resolution developmental studies in vivo
Simon Berger1, Evelyn Lattmann, Tinri Aegerter-Wilmsen
1Institute of Chemical and Bioengineering, ETH Zurich, 8093 Zurich, Switzerland. andrew.demello@chem.ethz.ch xavier.casadevall@chem.ethz.ch.
This correction clarifies a previous study on long-term Caenorhabditis elegans immobilization. The updated information ensures accurate high-resolution in vivo developmental studies are reproducible.
Area of Science:
- Developmental Biology
- Biophysics
- Microfluidics
Background:
- Accurate observation of Caenorhabditis elegans (C. elegans) development in vivo is crucial for understanding biological processes.
- Previous methods for immobilizing C. elegans for high-resolution imaging faced limitations in duration and potential artifacts.
Purpose of the Study:
- To provide a correction to a previously published study concerning long-term immobilization of C. elegans.
- To ensure the accuracy and reproducibility of high-resolution in vivo developmental studies using C. elegans.
Main Methods:
- The correction pertains to methods for immobilizing C. elegans within microfluidic devices.
- Details regarding the immobilization technique and its impact on developmental studies are addressed.
Main Results:
- The correction ensures that the reported high-resolution developmental data obtained through immobilization is accurately presented.
- Clarification is provided on the long-term stability and effectiveness of the immobilization technique.
Conclusions:
- Accurate long-term immobilization of C. elegans is essential for detailed in vivo developmental analysis.
- This correction refines the understanding of the methodology, supporting robust research in C. elegans biology.
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