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Updated: Feb 9, 2026

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Birth Defects in Northern Iran (2008-2013)
Arezoo Mirfazeli1, Nafiseh Kaviany1, Kanizreza Hosseinpoor1
1Gorgan Congenital Malformations Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Iranian Journal of Public Health
|May 31, 2018
Summary
This study found a birth defect prevalence of 11.66 per 1000 live births in Golestan Province, Iran. Cardiovascular system anomalies were the most frequent congenital anomalies observed.
Area of Science:
- Medical research
- Public health
- Epidemiology
Background:
- Congenital anomalies represent significant global health challenges.
- Understanding the geographic and temporal variations in birth defect patterns is crucial.
- This study focused on the prevalence and patterns of birth defects in Golestan Province, Iran.
Purpose of the Study:
- To investigate the live birth prevalence of congenital anomalies in Golestan Province, Iran.
- To determine the occurrence patterns of various birth defects within the studied population.
- To compare the findings with national and international data.
Main Methods:
- A cross-sectional descriptive study involving 144,920 live newborns from 2008 to 2013.
- Newborn examinations for birth defects and maternal interviews for demographic data.
- Utilized the International Classification of Diseases 10th revision-clinical modification (ICD-10-CM) for coding defects.
Main Results:
- A total of 1690 infants had birth defects, yielding a prevalence of 11.66 per 1000 live births.
- Cardiovascular system anomalies were the most common, with a prevalence of 8.34 per 1000 live births.
- Prevalence rates varied slightly among different ethnic groups (Fars, Turkmen, Sistani).
Conclusions:
- The birth defect prevalence in Golestan Province is lower than the Iranian average (20.3/1000) but higher than some Asian regions (7.33/1000).
- Findings highlight the importance of regional surveillance for congenital anomalies.
- Further research into contributing factors for observed patterns is warranted.
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