Self-resolving superficial primary cutaneous mucormycosis in a 7-week-old infant

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Milissa U Jones1, Michelle S Flores1, Rasheda J Vereen1

  • 1Department of Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, USA.

Pediatric Dermatology
|May 31, 2018
PubMed

Insights

A premature infant developed a skin rash after bandage removal, diagnosed as Rhizopus-related fungal infection. The condition resolved spontaneously without treatment, highlighting varied mucormycosis presentations.

Area of Science:

  • Medical Mycology
  • Neonatal Dermatology
  • Infectious Diseases

Background:

  • Premature infants, particularly those born at 30 weeks' gestational age, are considered vulnerable to infections.
  • Skin lesions in neonates require careful evaluation to differentiate between common and rare etiologies.
  • Mucormycosis is a rare but serious fungal infection, often associated with immunocompromised states.

Observation:

  • A 7-week-old premature infant presented with vesicular skin lesions after a 4-day bandage application.
  • Punch biopsy of the lesions revealed fungal elements.
  • Fungal elements were identified as Rhizopus species, indicating a cutaneous mucormycosis infection.

Findings:

  • The cutaneous mucormycosis in this infant demonstrated a self-resolving course.
  • No specific antifungal treatment was required for the Rhizopus infection.
  • Complete resolution of the skin lesions occurred within one month.

Implications:

  • Clinicians should consider mucormycosis in the differential diagnosis of skin eruptions in vulnerable neonates.
  • The presentation of fungal skin infections can be variable and may not always require aggressive treatment.
  • Early recognition and appropriate diagnostic procedures are crucial for managing neonatal fungal infections.

Keywords:
Rhizopusadhesivecutaneousinfantmucormycosisrash

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