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Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms

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A Structural View on Medicinal Chemistry Strategies against Drug Resistance

Stefano Agnello1, Michael Brand1, Mathieu F Chellat1

  • 1Institute of Chemistry and Biotechnology, Center for Organic and Medicinal Chemistry, Zurich University of Applied Sciences (ZHAW), Einsiedlerstrasse 31, 8820, Wädenswil, Switzerland.

Angewandte Chemie (International Ed. in English)
|May 31, 2018
PubMed

Keywords:
drug discoverydrug resistancemedicinal chemistrystructure-activity relationshipsstructure-based drug design

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