Related Experiment Video
Updated: Feb 9, 2026
07:41
Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
9.6K
CBD: a biomarker database for colorectal cancer.
Xueli Zhang1,2, Xiao-Feng Sun3, Yang Cao4,5
1School of Medicine, Institute of Medical Sciences, Örebro University, SE 70182 Örebro, Sweden.
Summary
A Colorectal cancer (CRC) biomarker database (CBD) was created using 870 biomarkers from 1115 articles. This tool offers comprehensive data for advancing CRC biomarker research and clinical applications.
Area of Science:
- Biomedical Informatics
- Oncology
- Bioinformatics
Background:
- Colorectal cancer (CRC) research requires extensive data on biomarkers.
- Existing resources may lack comprehensive, curated information on CRC biomarkers.
- Efficient tools are needed to support researchers in identifying and utilizing CRC biomarkers.
Purpose of the Study:
- To establish a centralized, searchable database of Colorectal cancer (CRC) biomarkers.
- To provide a comprehensive resource for researchers investigating CRC biomarkers for diagnosis, treatment, and prognosis.
- To create a collaborative platform for CRC researchers to share findings and advance research.
Main Methods:
- Data compilation from 1115 PubMed articles published between 1986 and 2017.
- Inclusion of 870 identified CRC biomarkers with detailed information.
- Database construction using MySQL, with a web interface developed in HTML, PHP, and JavaScript, hosted on an Apache HTTP server.
Main Results:
- The Colorectal cancer (CRC) biomarker database (CBD) contains curated information on 870 biomarkers.
- Data is categorized by biological properties, source, application, experimental methods, results, and cohort demographics.
- The database provides detailed information on biomarker utility in CRC diagnosis, treatment, and prognosis.
Conclusions:
- The CBD serves as a powerful, time-saving tool for comprehensive and accurate CRC biomarker research.
- The database facilitates communication and idea exchange among researchers, promoting high-quality CRC research.
- The CBD is a valuable resource for advancing the understanding and management of Colorectal cancer.
Related Concept Videos
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
905
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
905
02:18Cancer
54.4K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
54.4K
02:12What is Cancer?
14.5K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
14.5K
02:59Cancer Prevention
8.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
8.2K
02:49Cancer Therapies
10.2K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.2K
01:30Cancer Vaccines
1.1K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.1K