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Two Brothers With Dextro-Transposition of the Great Arteries
Joshua D Kurtz1,2, Katerina Boucek3,2, Minoo Kavarana4
1Division of Cardiology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.
Abstract:
Dextro-transposition of the great arteries (d-TGA) is a common cause of cyanotic heart disease in neonates. Current thought is d-TGA is a sporadic occurrence in families with an unclear etiology. We describe a case of brothers with d-TGA. Genetic testing revealed that both are heterozygous for two gene variations that are associated with congenital heart disease.
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