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Posterior Reversible Encephalopathy Syndrome Presenting as Stroke Mimic
Daniel Frick1, Martin Huecker1, Hugh Shoff1
1University of Louisville School of Medicine, Department of Emergency Medicine, Louisville, Kentucky.
Posterior reversible encephalopathy syndrome (PRES) can mimic stroke in end-stage renal disease patients presenting with neurological symptoms. Prompt diagnosis and treatment lead to full recovery, highlighting PRES as an under-recognized emergency department diagnosis.
Area of Science:
- Neurology
- Nephrology
- Emergency Medicine
Background:
- End-stage renal disease (ESRD) is a complex condition often associated with neurological complications.
- Patients with ESRD presenting to the emergency department (ED) with acute neurological deficits require careful evaluation to differentiate various etiologies.
Observation:
- A 33-year-old male with ESRD presented to the ED with headache, dizziness, and unilateral weakness, initially raising concern for stroke.
- Magnetic resonance imaging (MRI) revealed findings consistent with posterior reversible encephalopathy syndrome (PRES).
Findings:
- PRES was confirmed as the diagnosis in this ESRD patient with stroke-like symptoms.
- The patient received appropriate treatment for PRES and achieved a complete neurologic recovery.
Implications:
- PRES is an under-recognized condition in the ED that can be mistaken for stroke.
- Misdiagnosis of PRES as stroke may lead to inappropriate diagnostic pathways and potential iatrogenic harm.
- Increased awareness of PRES in ESRD patients is crucial for timely and accurate diagnosis and management.
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