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When Too Much Is Enough: Pediatric Cyproheptadine Overdose with Confirmatory Level
Terrance McGovern1, Justin McNamee2, Steven Marcus3
1St. Joseph's Regional Medical Center, Department of Emergency Medicine, Paterson, New Jersey.
Clinical Practice and Cases in Emergency Medicine
|June 1, 2018
Summary
This case report details a rare pediatric cyproheptadine overdose. A confirmed cyproheptadine level validated the overdose event in a child.
Area of Science:
- Pharmacology
- Toxicology
- Pediatrics
Background:
- Cyproheptadine is an H-1 antihistamine with anticholinergic and antiserotonergic properties.
- Commonly used for cold-induced urticaria and appetite stimulation.
- Emerging interest in its use for drug-induced serotonin syndrome.
Observation:
- This report describes an uncommon case of cyproheptadine overdose.
- The patient was a pediatric individual.
- A confirmatory blood cyproheptadine level was obtained.
Findings:
- The case confirms a rare instance of cyproheptadine overdose in a pediatric patient.
- Laboratory analysis verified the presence of elevated cyproheptadine levels.
Implications:
- Highlights the potential for cyproheptadine toxicity, even in pediatric populations.
- Underscores the importance of monitoring cyproheptadine levels in suspected overdose cases.
- Contributes to the limited literature on cyproheptadine overdose management.
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