Related Experiment Video

Updated: Sep 10, 2026

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
12:19

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli

Published on: June 27, 2015

Na-K-ATPase in isolated rabbit tubules after unilateral nephrectomy and Na+ loading

P Scherzer, H Wald, J W Czaczkes

    The American Journal of Physiology
    |April 1, 1985
    PubMed

    Keywords:
    renal compensationtubular transportsodium homeostasiskidney physiology

    More Related Videos

    Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium08:46

    Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium

    Published on: September 1, 2015

    A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion09:02

    A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

    Published on: February 2, 2021

    Related Concept Videos

    ATP Driven Pumps III: V-type Pumps01:30

    ATP Driven Pumps III: V-type Pumps

    V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
    The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
    Tubular Reabsorption and Secretion01:28

    Tubular Reabsorption and Secretion

    Tubular secretion and reabsorption are two critical processes in the nephron tubule of the kidneys. When the fluid filtered from the glomerulus enters the proximal convoluted tubule, it is referred to as filtrate, and its composition changes due to tubular reabsorption and secretion.
    Tubular reabsorption is a selective process that starts when the filtrate enters the proximal tubules. It involves substances traveling through the transcellular route (through the tubule cell and peritubular...
    Reabsorption and Secretion in the Loop of Henle01:17

    Reabsorption and Secretion in the Loop of Henle

    The thick ascending limb of the nephron loop has Na+–K+–2Cl− symporters in the apical membranes of its cells. These symporters simultaneously reclaim one sodium ion, one potassium ion, and two chloride ions from the tubular fluid. Sodium ions are actively transported into the interstitial fluid at the base and sides of the cell, diffusing into the vasa recta. Chloride ions move through leakage channels in the basolateral membrane into the interstitial fluid and then into the vasa recta.
    Renal Drug Excretion: Tubular Secretion01:28

    Renal Drug Excretion: Tubular Secretion

    Active tubular secretion is a robust, energy-demanding process that utilizes carrier systems to transport drugs into renal tubules. The active renal secretion systems include the organic anion transporter (OAT) for weak acids and the organic cation transporter (OCT) for weak bases. Structurally similar drugs can compete for the same transporter, potentially leading to drug accumulation and toxicity. However, this principle can be exploited therapeutically. One example is probenecid (Probalan),...
    Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion01:22

    Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion

    The kidneys maintain homeostasis through filtration, reabsorption, and secretion. Tubular reabsorption and secretion are crucial in forming urine and regulating electrolytes, water balance, and waste elimination.Tubular Reabsorption and Secretion ProcessesTubular reabsorption is the process that reclaims essential substances such as electrolytes, glucose, amino acids, and water from the glomerular filtrate back into the bloodstream. This is achieved through passive and active transport...
    Acute Kidney Injury II: Pathophysiology01:29

    Acute Kidney Injury II: Pathophysiology

    Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...