Related Experiment Video
Updated: Feb 9, 2026

Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
Published on: October 22, 2015
Adequate nutrition status important for bone mineral density improvement in a patient with anorexia nervosa
Yukio Nakamura1,2, Mikio Kamimura3, Hidefumi Koiwai4
1Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Abstract:
Low bone mineral density (BMD) is one of the most frequent complications of anorexia nervosa (AN). We report the clinical outcomes of a female patient with severe AN, whose chest had become deformed due to thoracic fracture. Lumbar BMD was 0.358 g/cm2 (T-score = -6.3), and total hip BMD was 0.411 g/cm2 (T-score = -4.4). Active vitamin D increased these parameters by 81.0% and 57.4%, respectively, but a drop in her nutrition status afterward resulted in a sharp decrease in BMD values. These findings suggest that adequate nutrient intake is essential for effective osteoporosis treatment in patients with AN.
Related Concept Videos
Anorexia Nervosa
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
The Roles of Bacteria and Fungi in Plant Nutrition
Bulimia Nervosa
Water and Mineral Acquisition
Minerals
Major...

