Crystal structure of 4-(pyrazin-2-yl)morpholine

Area of Science:

• Crystallography
• Molecular Chemistry
• Organic Chemistry

Background:

• Understanding molecular interactions is key in crystal engineering.
• The morpholine and pyrazine moieties are common in biologically active compounds.

Purpose of the Study:

• To elucidate the crystal structure of the title compound (C8H11N3O).
• To investigate the intermolecular interactions governing crystal packing.

Main Methods:

• Single-crystal X-ray diffraction was employed.
• Analysis of crystallographic data to determine molecular and crystal structure.

Main Results:

• The compound C8H11N3O exhibits a nearly planar molecular structure.
• Crystal packing is characterized by sheet formation parallel to the b axis.
• Non-classical hydrogen bonds involving C-H, morpholine oxygen, and pyrazine nitrogen stabilize the structure.
• The compound crystallizes in the monoclinic space group P21/c with Z=4.

Conclusions:

• The study provides detailed insights into the solid-state structure of C8H11N3O.
• The identified hydrogen bonding network is crucial for the observed crystal architecture.
• This structural information can aid in the design of related compounds.