Related Experiment Video
Updated: Feb 9, 2026

Clinical Application of Microscope-Assisted Minimally Invasive Anterior Lumbar Interbody Fusion
Published on: June 16, 2023
Spinal Biologics in Minimally Invasive Lumbar Surgery
Kevin Y Chang1, Wellington K Hsu1
1Department of Orthopedic Surgery, Northwestern University Feinberg School of Medicine, 676 N. Saint Clair St., Suite #1350, Chicago, IL 60611, USA.
Abstract:
As the use of minimally invasive spine (MIS) fusion approaches continues to grow, increased scrutiny is being placed on its outcomes and efficacies against traditional open fusion surgeries. While there are many factors that contribute to the success of achieving spinal arthrodesis, selecting the optimal fusion biologic remains a top priority. With an ever-expanding market of bone graft substitutes, it is important to evaluate each of their use as it pertains to MIS techniques. This review will summarize the important characteristics and properties of various spinal biologics used in minimally invasive lumbar surgeries and compare their fusion rates via a systematic review of published literature.
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