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Isolated Pancreatic Tuberculosis Mimicking Pancreatic Cancer: A Diagnostic Challenge
Abhishek Bhurwal1, Muhammad Masoodul Haq1, Sunil Sapru1
1Department of Internal Medicine, Saint Barnabas Medical Center, RWJBarnabas Health, West Orange, NJ, USA.
Isolated pancreatic tuberculosis, though rare, can mimic pancreatic cancer. Early diagnosis via endoscopic ultrasound with fine-needle aspiration and prompt antituberculosis therapy ensures successful treatment and avoids surgery.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Oncology
Background:
- Abdominal tuberculosis is a common extrapulmonary manifestation.
- Isolated pancreatic tuberculosis is exceptionally rare, even in endemic regions.
Observation:
- A case of isolated pancreatic tuberculosis presented as a pancreatic mass.
- Symptoms included persistent abdominal pain and jaundice.
- The mass was clinically and radiologically indistinguishable from malignant pancreatic tumors.
Findings:
- Endoscopic ultrasound with fine-needle aspiration (EUS-FNA) confirmed the diagnosis.
- Acid-fast bacilli were identified in tissue samples.
- Mycobacterium tuberculosis grew in cultures, confirming tuberculosis.
Implications:
- Early diagnosis and conservative management with antituberculosis therapy (ATT) are crucial.
- Prompt treatment can prevent unnecessary surgery and associated morbidity.
- Accurate diagnosis is vital due to differing prognoses and treatments for tuberculosis versus malignancy.
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