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MS-Based Analytical Techniques: Advances in Spray-Based Methods and EI-LC-MS Applications.

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This review highlights advancements in mass spectrometry (MS) for detecting organic compounds, focusing on real-time analysis for food safety and environmental applications. It surveys innovations in spray-based MS methods from 2012-2017.

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Area of Science:

  • Analytical Chemistry
  • Spectroscopy

Background:

  • Mass spectrometry (MS) is crucial for identifying organic compounds, offering molecular weight and structural data.
  • MS applications are growing in food safety, environmental, and forensic science for simultaneous targeted and nontargeted compound detection.
  • Real-time analytical methods are essential for early identification of safety risks.

Purpose of the Study:

  • To review instrumental innovations in mass spectrometry.
  • To focus on spray-based MS methods and their applications.
  • To cover the state-of-the-art in MS from 2012 to 2017, particularly for food analysis.

Main Methods:

  • Literature review of instrumental innovations in mass spectrometry.
  • Focus on spray-based MS techniques.
  • Analysis of applications in food safety, environmental, and forensic investigations.

Main Results:

  • Significant advancements in MS instrumentation enable real-time analysis in native environments.
  • Spray-based MS methods show promise for generating highly informative spectra.
  • The review covers key developments and applications between 2012 and 2017.

Conclusions:

  • Mass spectrometry innovations are enhancing capabilities for rapid and detailed organic compound analysis.
  • Real-time MS is increasingly vital for critical safety and environmental monitoring.
  • Spray-based MS techniques represent a key area of development for future applications.