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Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
Published on: July 1, 2021
18F-FDG PET/MRI in the diagnosis of an infected aortic aneurysm
Anna M Sailer1,2, Frans C Bakers1, Jan W Daemen3
1Department of Radiology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Abstract:
We report a case where an integrated whole body 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/magnetic resonance imaging (MRI) is performed in the diagnostic work-up of a saccular aortic aneurysm. The integrated whole body 18F-FDG PET/MRI study answered all relevant diagnostic questions, clearly marking an infected aortic aneurysm, depicting the extent of the infected area in relation to the aortic branch vessels, and indicating the aortic lesion as the primary site of infection. The patient was successfully treated by open type V TAAA repair and pericardial graft replacement. Aortic wall infection was proven in cultures of the surgical specimen.
Insights
Integrated whole-body 18F-fluorodeoxyglucose (18F-FDG) PET/MRI successfully diagnosed an infected aortic aneurysm. This imaging approach precisely located the infection and guided successful surgical treatment.
Area of Science:
- Medical Imaging
- Cardiovascular Surgery
- Infectious Diseases
Background:
- Saccular aortic aneurysms pose diagnostic challenges, particularly in identifying infection.
- Early and accurate diagnosis is crucial for effective treatment and patient outcomes.
Observation:
- An integrated whole-body 18F-fluorodeoxyglucose (18F-FDG) PET/MRI was utilized for the diagnostic work-up of a saccular aortic aneurysm.
- The imaging study provided comprehensive information regarding the aneurysm's status.
Findings:
- The 18F-FDG PET/MRI clearly identified the aortic aneurysm as infected.
- The study precisely delineated the extent of the infection in relation to adjacent aortic branch vessels.
- The aortic lesion was confirmed as the primary source of infection.
Implications:
- Integrated PET/MRI is a valuable tool for diagnosing infected aortic aneurysms.
- Accurate localization of infection is essential for planning surgical interventions.
- Successful treatment involved open type V thoracoabdominal aortic aneurysm (TAAA) repair and pericardial graft replacement, with surgical cultures confirming aortic wall infection.
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