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An Intervention Target for Myocardial Fibrosis: Autophagy
Chunmiao Lu1, Yusong Yang1, Yaping Zhu2
1Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Abstract:
Myocardial fibrosis (MF) is the result of metabolic imbalance of collagen synthesis and metabolism, which is widespread in various cardiovascular diseases. Autophagy is a lysosomal degradation pathway which is highly conserved. In recent years, research on autophagy has been increasing and the researchers have also become cumulatively aware of the specified association between autophagy and MF. This review highlights the role of autophagy in MF and the potential effects through the administration of medicine.
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