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Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Common Ion Effect03:24

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Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Châtelier’s principle. Consider the dissolution of silver iodide:
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Increasing Function01:18

Increasing Function

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An increasing function exhibits a rise in output values as input values increase. This behavior is depicted graphically as a curve or line that slopes upward from left to right. Such a function satisfies the condition that if x1 < x2, then f(x1) < f(x2), indicating that the function values grow with increasing inputs. This concept is fundamental in understanding growth trends across various domains, such as population dynamics, financial investments, or resource consumption.The...
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pre-mRNA Processing02:01

pre-mRNA Processing

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In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a “cap” to the 5’ end of the growing transcript. In this process, a 5’ phosphate is replaced by modified guanosine that has a methyl group attached to it (7-Methyl...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Pre-mRNA Processing: Modification of pre-mRNA Ends01:35

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In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
Once about 20-40 ribonucleotides have been joined together by RNA polymerase, a group of enzymes adds a cap to the 5' end of the growing transcript. In this process, a 5' phosphate is replaced by modified guanosine that has a methyl group attached (7-methyl guanosine). This 5' cap helps...
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Related Experiment Video

Updated: Feb 9, 2026

SUMO-Binding Entities SUBEs as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer
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[Pre-gestational diabetes : an increasingly common entity].

Karim Gariani1,2, Agnès Ditisheim1,2,3, Michel Boulvain2,3

  • 1Service d'endocrinologie, diabétologie, hypertension et nutrition, HUG, 1211 Genève 14.

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Pre-gestational diabetes, the presence of diabetes before pregnancy, is increasing. Optimal glycemic control before and during pregnancy is crucial for minimizing risks to both mother and fetus.

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Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Public Health

Context:

  • Pre-gestational diabetes is a growing concern in reproductive health.
  • Increasing prevalence necessitates optimized management strategies.

Purpose:

  • To highlight the importance of glycemic control in pre-gestational diabetes.
  • To emphasize continuous adaptation of treatment during pregnancy.

Summary:

  • Management involves pre-conception glycemic optimization and ongoing adaptation during gestation.
  • Close monitoring and control are vital for maternal and fetal well-being.

Impact:

  • Aims to reduce maternal and fetal complications associated with pre-gestational diabetes.
  • Informs clinical practice for improved pregnancy outcomes.