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Updated: Feb 9, 2026

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In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
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Renal mass biopsy: an oncological conundrum
Roshan M Patel1, Egor Parkhomenko, Kamaljot S Kaler
1Department of Urology, University of California, Irvine, Orange, California, USA.
Current Opinion in Urology
|June 1, 2018
Summary
Urologists rarely biopsy small renal masses (SRMs) due to safety and efficacy concerns. However, renal mass biopsy is safe, effective, and cost-efficient, warranting its integration into standard T1a SRM care.
Area of Science:
- Urology
- Oncology
- Diagnostic Medicine
Background:
- Small renal masses (SRMs) are frequently encountered.
- Urologists often hesitate to biopsy T1a SRMs, impacting diagnostic and treatment pathways.
Purpose of the Study:
- To investigate the reasons behind the infrequent biopsy of T1a small renal masses (SRMs).
- To advocate for the routine use of renal mass biopsy in SRM management.
Main Methods:
- Review of current urological practices and literature regarding SRM biopsy.
- Comparative analysis of SRM biopsy safety and efficacy against biopsies of other organ system neoplasms.
Main Results:
- Urologists express concerns about biopsy safety and efficacy, leading to infrequent use.
- SRM biopsy demonstrates favorable safety and efficacy profiles comparable to other organ systems.
- Renal mass biopsy is cost-effective and can be performed in an office setting, reducing healthcare costs.
Conclusions:
- Renal mass biopsy is a crucial tool for T1a SRM decision-making.
- Tissue-specific diagnosis via biopsy should be the standard of care for SRMs.
- Integrating biopsy into practice aligns urology with standards in other organ systems.
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