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Updated: Feb 9, 2026

Diaphragmatic Ultrasound in Adults: Image Acquisition and Interpretation
Published on: January 31, 2025
Diaphragmatic ultrasonography for predicting ventilator weaning: A meta-analysis
Caifeng Li1, Xin Li, Hongqiu Han
1Intensive Care Unit Department of Cardiothoracic Surgery Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Diaphragmatic ultrasonography shows promise in predicting extubation success. This meta-analysis found it accurately identifies patients at risk of reintubation within 48 hours.
Area of Science:
- Critical Care Medicine
- Diagnostic Accuracy
- Pulmonary Medicine
Background:
- Weaning failure is a significant challenge in mechanically ventilated patients.
- The predictive value of diaphragmatic ultrasonography for weaning outcomes remains debated.
- This study aimed to evaluate diaphragmatic ultrasonography for predicting reintubation risk.
Purpose of the Study:
- To assess the diagnostic accuracy of diaphragmatic ultrasonography in predicting reintubation within 48 hours of extubation.
- To synthesize evidence from existing studies through a meta-analysis.
Main Methods:
- A comprehensive literature search was conducted across PubMed, Embase, and Cochrane Library.
- Included studies provided sufficient data for 2x2 contingency table construction.
- Methodological quality was assessed using QUADAS-2; meta-analysis employed fixed or random effects models.
Main Results:
- Thirteen studies involving 742 subjects were analyzed.
- Pooled sensitivities for diaphragm excursion (DE) and diaphragm thickness fraction (DTF) were 0.786 and 0.893, respectively.
- Pooled specificities were 0.711 (DE) and 0.796 (DTF), with AUCs of 0.8590 (DE) and 0.8381 (DTF).
Conclusions:
- Diaphragmatic ultrasonography is a potentially valuable tool for predicting reintubation risk post-extubation.
- Further large-scale studies are needed to confirm these findings due to observed heterogeneities.
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