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Updated: Feb 9, 2026

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Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
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Delayed Posttreatment Residual Flow into Aneurysm After Flow Diverter Placement
Ryuta Nakae1, Tomoji Takigawa1, Koji Hirata1
1Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center, Saitama, Japan.
World Neurosurgery
|June 1, 2018
Summary
Delayed residual flow into an aneurysm after flow diverter (FD) treatment may be a normal part of healing and does not always require additional intervention, as complete thrombosis can still occur.
Area of Science:
- Neuroendovascular surgery
- Cerebrovascular disease management
Background:
- Delayed aneurysmal rupture is a concern following flow diverter (FD) treatment due to assumed post-treatment inflow.
- The clinical significance of residual flow detected months after FD placement remains unclear.
Observation:
- A single Pipeline Embolization Device (PED) was used to treat a large intracranial aneurysm.
- Initial post-procedure angiography showed flow stagnation, but a 6-month follow-up revealed delayed residual flow into the aneurysm sac.
- The patient's planned re-intervention was deferred, and dual antiplatelet therapy was continued.
Findings:
- Despite delayed residual flow at 6 months, the aneurysm completely thrombosed by 12 months post-procedure.
- This case suggests that delayed residual flow may not impede eventual aneurysm occlusion.
Implications:
- Delayed residual flow post-FD placement might be a normal clinical course, not necessarily indicating a need for further intervention.
- Further research is required to determine optimal follow-up strategies and the necessity of additional procedures for patients with delayed residual flow.
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