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Updated: Feb 9, 2026

Bacterial Detection & Identification Using Electrochemical Sensors
Published on: April 23, 2013
A turn-on ESIPT based fluorescent sensor for detection of aluminum ion with bacterial cell imaging and logic gate
Neetu Yadav1, Ashok Kumar Singh1
1Department of Chemistry, Indian Institute of Technology, Roorkee 247667, India.
Abstract:
6-amino-5-(((2-hydroxynaphthalen-1-yl)methylene)amino)-2-mercaptopyrimidin-4-ol (L1) and 6-amino-5-((4-bromobenzylidene)amino)-2-mercaptopyrimidin-4-ol (L2) have been designed and characterized by various techniques such as UV-Vis, fluorescence, FT-IR, mass spectrometry and NMR spectroscopy. L1 was successfully applied for selective recognition of aluminum ion and showed "OFF-ON type" mode in the presence of Al3+ ion. The sensor was recommended for the selective detection of Al3+ with 1:1 stoichiometry by Job's plot in ACN medium. The high sensitivity of host L1 supports the high detection limit, 99 nM with good association constant. It was also used for bacterial cell imaging (E.coli DHα) and logic gate applications which was manifested the green and red fluorescent images with Al3+ion and represents INHIBIT logic gate in switching behavior.
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