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The relationship between monocyte/high-density lipoprotein ratio and Selvester QRS score in patients with STEMI

Lütfü Aşkın1, Mustafa Çetin, Serdar Türkmen

  • 1Department of Cardiology, Adıyaman University Training and Research Hospital, Adıyaman, Turkey. lutfuaskin23@gmail.com.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|June 2, 2018
PubMed

Insights

The monocyte-to-HDL ratio (MHR) is linked to higher QRS scores in ST-elevation myocardial infarction (STEMI) patients. This inflammation marker independently predicts QRS scores, aiding in prognosis assessment for heart attack patients.

Area of Science:

  • Cardiology
  • Biomarkers
  • Inflammation

Background:

  • The monocyte-to-high-density lipoprotein ratio (MHR) is a novel prognostic factor in cardiovascular disease.
  • The Selvester QRS score is valuable for predicting ST-elevation myocardial infarction (STEMI) prognosis.
  • The association between MHR and QRS score in STEMI patients remains unexplored.

Purpose of the Study:

  • To investigate the relationship between MHR and QRS score in patients diagnosed with STEMI.
  • To determine if MHR is an independent predictor of QRS score in STEMI.

Main Methods:

  • Retrospective analysis of 99 consecutive STEMI patients.
  • Serial measurements of MHR, monocyte count, and lipid panels.
  • Classification of patients into high (QRS score ≥6) and low (QRS score <6) groups.

Main Results:

  • MHR was significantly higher in the high QRS score group on day 1.
  • MHR was associated with QRS score in univariate analysis.
  • MHR independently predicted QRS score (OR: 0.390, p<0.001).

Conclusions:

  • Elevated MHR indicates inflammation and oxidative stress, correlating with higher QRS scores in STEMI.
  • MHR is an independent predictor of QRS scores in STEMI patients.
  • MHR may serve as a useful prognostic indicator in STEMI management.
Abstract

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