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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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Is subcutaneous fat tissue embolization effective and safe as a septal reduction technique in a patient with

Elnur Alizade, Sabahattin Gündüz, Ahmet Güner1

  • 1Department of Cardiology, Kartal Koşuyolu Heart Training and Research Hospital, İstanbul, Turkey. ahmetguner489@gmail.com.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|June 2, 2018
PubMed

Insights

Hypertrophic obstructive cardiomyopathy (HOCM) can be treated with septal reduction therapy. A novel technique successfully treated a 57-year-old female patient with HOCM, offering a new therapeutic option.

Area of Science:

  • Cardiology
  • Cardiac Surgery

Background:

  • Hypertrophic obstructive cardiomyopathy (HOCM) is an inherited cardiac condition characterized by left ventricular outflow tract (LVOT) obstruction.
  • The obstruction is typically caused by basal septal hypertrophy and systolic anterior motion of the anterior mitral valve leaflet.

Observation:

  • Septal reduction therapy aims to alleviate LVOT obstruction in HOCM patients.
  • Myectomy and transcoronary alcohol septal ablation are established treatments, but a new method has emerged.

Findings:

  • This case report details the successful application of a novel septal reduction technique in a 57-year-old female patient with HOCM.
  • The new technique effectively addressed the patient's left ventricular outflow tract obstruction.

Implications:

  • This novel septal reduction technique presents a promising alternative for HOCM management.
  • Further research into this new method could expand treatment options for patients unsuitable for traditional surgery.

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