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Updated: Feb 9, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Drug Induced Sleep Endoscopy Identification of Adenoid Regrowth in Pediatric Obstructive Sleep Apnea
Habib G Zalzal1, Michele Carr1, Nainika Nanda2
1Department of Otolaryngology, Head and Neck Surgery, West Virginia University School of Medicine, Morgantown, WV, USA.
Objective:
To establish the incidence and possible contributing factors leading to adenoid regrowth in children with pediatric sleep apnea using drug induced sleep endoscopy (DISE).
Methods:
Children treated for obstructive sleep apnea following previous adenoidectomy were evaluated using DISE. Adenoid regrowth was scored by the same attending physician using a 5-point grading scale. Age, sex, body mass index (BMI) percent for age, polysomnogram results, initial adenoid size before adenoidectomy, and postoperative complications were evaluated.
Results:
Fifty-six patients (age range 22 months to 16 years) met inclusion criteria. Twenty-five children (44.6%) had Grade 2 adenoid or larger. Mean age at the time of DISE was 7.11 years, with an average of 1.75 years since initial adenoidectomy. Mean preadenoidectomy size based on intraoperative nasopharyngeal mirror assessment was Grade 2.55 (95% CI 2.30-2.79). Adenoid size at time of sleep endoscopy was Grade 1.64 (95% CI 1.30-1.98). Characteristics associated with adenoid regrowth were higher body mass index for age percentile at time of endoscopy (P < 0.05), initial adenoid size (P < 0.01), and time between initial adenoidectomy and endoscopy (P = 0.05).
Conclusions:
Body mass index for age percentile, initial adenoid size, and time between initial adenoidectomy and drug induced sleep endoscopy correlate with regrowth in childhood obstructive sleep apnea.
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