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Updated: Feb 9, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Research on Improved Depth Belief Network-Based Prediction of Cardiovascular Diseases
Peng Lu1,2, Saidi Guo2,3, Hongpo Zhang2,4
1School of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, China.
Abstract:
Quantitative analysis and prediction can help to reduce the risk of cardiovascular disease. Quantitative prediction based on traditional model has low accuracy. The variance of model prediction based on shallow neural network is larger. In this paper, cardiovascular disease prediction model based on improved deep belief network (DBN) is proposed. Using the reconstruction error, the network depth is determined independently, and unsupervised training and supervised optimization are combined. It ensures the accuracy of model prediction while guaranteeing stability. Thirty experiments were performed independently on the Statlog (Heart) and Heart Disease Database data sets in the UCI database. Experimental results showed that the mean of prediction accuracy was 91.26% and 89.78%, respectively. The variance of prediction accuracy was 5.78 and 4.46, respectively.
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