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Updated: Feb 9, 2026

Cross-Modal Multivariate Pattern Analysis
Published on: November 9, 2011
Chemical Differentiation and Quantitative Analysis of Different Types of Panax Genus Stem-Leaf Based on a
Lele Li1, Yang Wang1, Yang Xiu1
1Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.
Abstract:
Two quantitative methods (-ESI full scan and -ESI PRM MS) were developed to analyze ginsenosides in ginseng stem-leaf by using UPLC-Q-Exactive Orbitrap/MS. By means of -ESI PRM MS method, the contents of eighteen ginsenosides in Asian ginseng stem-leaf (ASGSL) and American ginseng stem-leaf (AMGSL) were analyzed. The principal component analysis (PCA) model was built to discriminate Asian ginseng stem-leaf (ASGSL) from American ginseng stem-leaf (AMGSL) based on -ESI PRM MS data, and six ginsenosides (F11, Rf, R2, F1, Rb1, and Rb3) were obtained as the markers. To further explore the differences between cultivated ginseng stem-leaf and forest ginseng stem-leaf, the partial least squares-discriminant analysis (PLS-DA) model was built based on -ESI full scan data. And twenty-six markers were selected to discriminate cultivated ginseng stem-leaf (CGSL) from forest ginseng stem-leaf (FGSL). This study provides reliable and effective methods to quantify and discriminate among different types of ginseng stem-leaf in the commercial market.
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