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Updated: Feb 9, 2026

Isolation of Myeloid Dendritic Cells and Epithelial Cells from Human Thymus
Published on: September 19, 2013
Spindle epithelial tumor with thymus-like differentiation of the thyroid in a 70-year-old man
Sunhye Lee1, Yon Seon Kim2, Jeong Hyeon Lee3
1Department of Radiology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
Abstract:
Spindle epithelial tumor with thymus-like differentiation (SETTLE) is a very rare tumor of the thyroid gland mostly occurring in young patients. The imaging findings of SETTLE tumors are yet to be defined. However, they are usually described as well-defined heterogeneously enhanced masses on CT scan. The current case has the potential growth as compared with a 2009 chest radiography. We took into account the possibility of SETTLE in the case of a bulky mass in patients over 70 years old, particularly in the lower neck. Herein, we report a case of the oldest patient so far. The patient underwent a right lobectomy of the thyroid and mass excision. Follow-up CT scans after 6 months revealed no local recurrence. Surgery is the gold standard treatment for SETTLE. Chemotherapy and radiotherapy could be another possible option for patients with advanced stage SETTLE.
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